Record number :
808747
Title of article :
Homocysteine and cardiovascular disease: : Current evidence and future prospects
Author/Authors :
Arduino A. Mangoni، نويسنده , , Stephen H. D. Jackson، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Pages :
10
From page :
556
To page :
565
Abstract :
Hyperhomocysteinemia is an independent risk factor for cardiovascular disease. Despite the well-known effectiveness of vitamin supplementation in reducing homocysteine levels, it is not known whether lowering of homocysteine levels is associated with a reduction in cardiovascular morbidity and mortality. The aim of this review is to discuss the epidemiologic evidence about the relation between homocysteine and cardiovascular disease, the pathophysiologic mechanisms responsible for the deleterious vascular and hemostatic effects of homocysteine, and studies of the potential benefits of homocysteine-lowering therapy.
Journal title :
The American Journal of Medicine
Serial Year :
2002
Link To Document :
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