Record number :
798573
Title of article :
Optimized synthesis of aminooxy-peptides as glycoprobe precursors for surface-based sugar–protein interaction studies
Author/Authors :
Carmen Jiménez-Castells، نويسنده , , Beatriz G. de la Torre، نويسنده , , Ricardo Gutiérrez Gallego، نويسنده , , David Andreu، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Pages :
4
From page :
5155
To page :
5158
Abstract :
An improved procedure for solid phase coupling of Boc-aminooxyacetic acid to peptides is described. By avoiding base-containing activation mixtures which cause over-acylation, it practically suppresses this unwanted side reaction and leads to near quantitative yields of Aoa-peptides, useful as glycoprobe precursors in glycomic studies.
Keywords :
Glycoprobes , Aminooxy-peptide , Surface-based interaction studies , Coupling reagent
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2007
Link To Document :
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