Record number :
789838
Title of article :
An improved route to 1,2-dideoxy-β-1-phenyl- -ribofuranose
Author/Authors :
Uthai Wichai، نويسنده , , Stephen A. Woski، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Pages :
4
From page :
3465
To page :
3468
Abstract :
An efficient synthesis of the aryl nucleoside analogue 1,2-dideoxy-β-1-phenyl- -ribofuranose (1) is described. This route utilizes the addition of phenyllithium to a protected 2-deoxyribonolactone followed by reduction with triethylsilane/boron trifluoride etherate to selectively produce the β-anomer. Deprotection yields the desired aryl C-nucleoside in 27% overall yield from 2-deoxy- -ribose
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
1998
Link To Document :
بازگشت