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Title of article :
Severe acute liver damage in anorexia nervosa: two case reports
Author/Authors :
Carmela De Caprio، نويسنده , , Alessia Alfano، نويسنده , , Ignazio Senatore، نويسنده , , Luigi Zarrella، نويسنده , , FABRIZIO PASANISI، نويسنده , , FRANCO CONTALDO، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
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Abstract :
Objective Two female patients (18 and 30 y old, body mass indexes 14.1 and 13.2 kg/m2) with severe, restrictive anorexia nervosa developed sudden severe liver damage. In addition to overt protein-energy malnutrition, they showed marked hypotension, bradycardia, dry skin, acrocyanosis, and hypothermia. Most common causes of liver failure, such as hepatotropic viruses, hepatotoxic drugs, alcohol, cannabis, and cocaine abuse, were excluded. Methods Therapeutic intervention consisted of immediate plasma volume support, progressive parenteral or oral nutritional rehabilitation, and parenteral potassium and phosphorus supplements to avoid the refeeding syndrome. Results and conclusion Improvement of initial clinical symptoms and rapid recovery of liver enzymes after this type of treatment suggest that severe liver damage in anorexia nervosa may be secondary to acute hypoperfusion.
Keywords :
Liver damage , Anorexia nervosa , protein-energy malnutrition
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