Record number :
608670
Title of article :
Do Coronary Bypass Graft Flows Differ Between On-Pump and Off-Pump Operations?
Author/Authors :
Yves A.G. Louagie، نويسنده , , Jacques Jamart، نويسنده , , André Gruslin، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Pages :
9
From page :
2004
To page :
2012
Abstract :
Background The aim of this study is to compare hemodynamic factors in coronary bypass grafts on-pump and off-pump. Methods Two propensity score-matched groups of 89 patients each including 408 dual beam Doppler flow measurements were compared. The study included only patent and single terminolateral bypass grafts. Results Flow was 64.9 ± 37.3 mL/min in the on-pump group versus 58.6 ± 35.0 mL/min in the off-pump group (p = 0.063); velocity was 23.8 ± 10.5 versus 20.5 ± 10.4 cm/s (p = 0.004); resistance measured as mm Hg/(mL/min−1) was 1.50 ± 1.09 versus 1.76 ± 1.14 (p = 0.020); pulsatility index was 1.98 ± 1.52 versus 2.44 ± 1.62 (p = 0.004). The hematocrit was 23.5 ± 3.8% in the on-pump and 32.9 ± 4.1% in the off-pump groups (p< 0 0.001). Multivariate analysis showed that hematocrit was the most significant factor influencing flow (p< 0.001) and velocity (p< 0.001), along with resistance (p = 0.004) and pulsatility index (p< 0.001). In a subset of 50 hemodynamic measurements made on left internal thoracic arteries implanted onto left anterior descending arteries and matched for hematocrit, there were no differences between on-pump and off-pump groups regarding flow, velocity, resistance, or pulsatility index. Conclusions Off-pump compared with on-pump bypass surgery is associated with lower velocity and higher resistance in the grafts, mainly caused by changes in hematocrit and viscosity related to hemodilution.
Journal title :
The Annals of Thoracic Surgery
Journal title :
The Annals of Thoracic Surgery
Serial Year :
2005
Link To Document :
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