Title of article :
Usefulness of 64-Slice Multislice Computed Tomography Coronary Angiography to Assess In-Stent Restenosis Original Research Article
*† Filippo Cademartiri، نويسنده , , Joanne D. Schuijf، نويسنده , , Francesca Pugliese، نويسنده , , Nico R. Mollet، نويسنده , , J. Wouter Jukema، نويسنده , , Erica Maffei، نويسنده , , Lucia J. Kroft، نويسنده , , Alessandro Palumbo، نويسنده , , Diego Ardissino، نويسنده , , Patrick W. Serruys، نويسنده , , * Gabriel P. Krestin، نويسنده , , Ernst E. van der Wall، نويسنده , , Pim J. De Feyter، نويسنده , , Jeroen J. Bax، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
This study sought to evaluate the diagnostic accuracy of 64-slice multislice computed tomography (MSCT) coronary angiography in the follow-up of patients with previous coronary stent implantation.
Recent investigations have shown increased image quality and diagnostic accuracy for noninvasive coronary angiography with 64-slice MSCT as compared with previous-generation MSCT scanners, but data on the evaluation of coronary stents are scarce.
In 182 patients (152 [84%] male, ages 58 ± 11 years) with previous stent (≥2.5 mm diameter) implantation (n = 192), 64-slice MSCT angiography using either a Sensation 64 (Siemens, Forchheim, Germany) or Aquilion 64 (Toshiba, Otawara, Japan) was performed. At each center, coronary stents were evaluated by 2 experienced observers and evaluated for the presence of significant (≥50%) in-stent restenosis. Quantitative coronary angiography served as the standard of reference.
A total of 14 (7.3%) stented segments were excluded because of poor image quality. In the interpretable stents, 20 of the 178 (11.2%) evaluated stents were significantly diseased, of which 19 were correctly detected by 64-slice MSCT. Accordingly, sensitivity, specificity, and positive and negative predictive value to identify in-stent restenosis in interpretable stents were 95.0% (95% confidence interval [CI] 85% to 100%), 93.0% (95% CI 90% to 97%), 63.3% (95% CI 46% to 81%), and 99.3% (95% CI 98% to 100%), respectively.
In-stent restenosis can be evaluated with 64-slice MSCT with good diagnostic accuracy. In particular, a high negative predictive value of 99% was observed, indicating that 64-slice MSCT may be most valuable as a noninvasive method of excluding in-stent restenosis.
CI , Confidence interval , ECG , Electrocardiogram , MSCT , multislice computed tomography
Journal title :
JACC (Journal of the American College of Cardiology)