Record number :
2536513
Title of article :
An electrochemical sensor based on multi-walled carbon nanotubes and 4-(((4- mercaptophenyl)imino)methyl) benzene-1,2-diol for simultaneous determination of epinephrine in the presence of acetaminophen
Author/Authors :
aghaei, roghayyeh yazd university - faculty of science - department of chemistry, Yazd, Iran , mazloum-ardakani, mohammad yazd university - faculty of science - department of chemistry, Yazd, Iran , abdollahi-alibeik, mohammad yazd university - faculty of science - department of chemistry, Yazd, Iran , moaddeli, ali yazd university - faculty of science - department of chemistry, Yazd, Iran
From page :
139
To page :
148
Abstract :
A carbon paste electrode modified with 4-(((4-mercaptophenyl)imino)methyl)benzene-1,2-diol (MIB) and multi-walled carbon nanotubes (MIB /CNT/CPE) was prepared for determination of epinephrine (EP) in the presence of acetaminophen (AC). Cyclic voltammetry, chronoamperometry, and differential pulse voltammetry (DPV) techniques were used to investigate the modified electrode for the electrocatalytic oxidation of EP and AC in aqueous solutions. The separation of the oxidation peak potential for EP- AC was 200 mV. Under the optimum conditions, the calibration curve for EP was obtained in the range of 1.0 to 25.0 μM and 25.0 to 500.0 μM. The diffusion coefficient for the oxidation of EP at the surface of the modified electrode was calculated as 5.76×10^-5 cm^2 s^-1.
Keywords :
Acetaminophen , Carbon nanotubes , Carbon paste electrode , Epinephrine
Journal title :
Trends in Pharmaceutical Sciences
Link To Document :
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