Title of article :
Practical Difficulties in Estimating The Prevalence of Primary Infertility in Iran
Akhondi, Mohammad Mehdi Department of Embryology- Reproductive Biomedicine Research Center- Royan Institute for Reproductive Biomedicine- ACECR, Tehran , Ranjbar, Fahime Nursing Care Research Center - Iran University of Medical Sciences, Tehran , Shirzad, Mahdi Reproductive Biotechnology Research Center- Avicenna Research Institute- ACECR, Tehran , Behjati Ardakani, Zohre Reproductive Biotechnology Research Center- Avicenna Research Institute- ACECR, Tehran , Kamali, Koorosh Department of Public Health- School of Public Health, Zanjan University of Medical Sciences , Mohammad, Kazem Department of Epidemiology and Biostatistics- School of Public Health- Tehran University of Medical Sciences
Background: According to the World Health Organization (WHO)'s clinical, epidemiological and demographic definitions,
infertility is an inability to become pregnant within one, two or five years of exposure to pregnancy, respectively.
Inconsistent infertility-related definitions and various methodological approaches make it difficult to compare
quantitative data in this regard and consequently, have negatively influenced estimating the prevalence of infertility.
The present study reviewed the results of a large population-based survey on how the clinical, epidemiological and demographic
definitions of infertility produce different results in terms of infertility prevalence in Iran and subsequently,
compared the findings in order to find the right time of treatment-seeking by couples.
Materials and Methods: This community-based, cross-sectional study was carried out by Avicenna Research Institute
in the urban and rural parts of Iran between 2010 and 2011. Using cluster sampling, the reproductive history of
17,187 married women aged 20-40 years, was recorded. Totally, 1011 clusters were randomly selected according to
post office codes, proportional to the population of the province. Descriptive and inferential statistical analysis of the
data was carried out by SPSS statistical software.
Results: The prevalence of primary infertility based on the WHO’s clinical, epidemiological and demographic definitions
were 20.2, 12.8 and 9.2%, respectively. In addition, secondary infertility rate was 4.9%.
Conclusion: Infertility estimates over a two-year exposure period made a 50% decrease in infertility rate; however,
increasing exposure period to five years made no significant difference in infertility rate. The findings showed that most
of the couples will get pregnant within two years of unprotected sexual intercourse and thus, need no treatment. Due to
practical difficulties in estimating the prevalence of primary infertility, the reference limit for time to pregnancy, should
be reconsidered and giving more time to younger women to become pregnant, seems reasonable.
Reproduction , Epidemiology , Infertility , Iran , Prevalence
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