Record number :
2445229
Title of article :
Aqueous Extract of Anethum Graveolens L. has Potential Antioxidant and Antiglycation Effects
Author/Authors :
Abbasi Oshaghi, Ebrahim Department of Clinical Biochemistry - School of Medicine - Hamadan University of Medical Sciences - Hamadan, Iran - 2Research Center for Molecular Medicine - Hamadan University of Medical Sciences - Hamadan , Khodadadi, Iraj Department of Clinical Biochemistry - School of Medicine - Hamadan University of Medical Sciences - Hamadan, Iran - 2Research Center for Molecular Medicine - Hamadan University of Medical Sciences - Hamadan , Tavilani, Heidar Department of Clinical Biochemistry - School of Medicine - Hamadan University of Medical Sciences - Hamadan, Iran - 2Research Center for Molecular Medicine - Hamadan University of Medical Sciences - Hamadan , Goodarzi, Mohammad Taghi Department of Clinical Biochemistry - School of Medicine - Hamadan University of Medical Sciences - Hamadan, Iran - 2Research Center for Molecular Medicine - Hamadan University of Medical Sciences - Hamadan
Pages :
6
From page :
328
To page :
333
Abstract :
The aim of this study was to assess the antiglycation and antioxidant properties of aqueous extract of Anethum graveolens (dill). In the in vivo and in vitro experiments, antioxidant properties, blood glucose, and AGEs formation were determined. Dill extract was given orally to healthy and diabetic rats. Our results illustrated that different concentrations of dill extract (0.125, 0.25, 0.5, and 1 mg/ml) have potential antiradical and antioxidant activity. Aqueous extract of dill significantly reduced AGEs formation and fructosamine levels, protein carbonyl and also thiol group’s oxidation, amyloid cross-β and fragmentation. After 2 months, blood glucose levels (P=0.006) and AGEs formation (P=0.003) significantly reduced in dill treated group compared with untreated diabetic animals. In conclusion, dill can be recommended as herbal medicine for the control and prevention of diabetic complications.
Keywords :
Anethum graveolens , Antioxidants , Herbal medicine , Hypoglycemic agents
Journal title :
Astroparticle Physics
Serial Year :
2016
Link To Document :
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