Record number :
2065002
Title of article :
Rare ocular and skin lesions of Marginal Zone Lymphoma
Author/Authors :
آلتيني، كرينا نويسنده Nuclear Medicine Unit, DIM., University of Bari “Aldo Moro”, Bari, Italy Altini, Corinna , اسابلا، آرتور نيكلي نويسنده Nuclear Medicine Unit, DIM., University of Bari “Aldo Moro”, Bari, Italy Asabella, Artor Niccoli , فراري، كريستينا نويسنده Nuclear Medicine Unit, DIM., University of Bari “Aldo Moro”, Bari, Italy Ferrari, Cristina , رابيني، دومنيكو نويسنده Nuclear Medicine Unit, DIM., University of Bari “Aldo Moro”, Bari, Italy Rubini, Domenico , جنتيل، آنتونيا نويسنده Pathological Anatomy Unit, DAP, University of Bari “Aldo Moro”, Bari, Italy Gentile, Antonia , رابيني، جيوسپ نويسنده Nuclear Medicine Unit, DIM., University of Bari “Aldo Moro”, Bari, Italy Rubini, Giuseppe
Issue Information :
فصلنامه با شماره پیاپی 42 سال 2014
Pages :
5
From page :
89
To page :
93
Abstract :
We report a case of a 75-year old man that came at hematologist’s attention for lymphoma evaluation due to axillary lymph node enlargement and fever. Thorax, abdomen and pelvis Contrast-Enhanced Computed Tomography (CECT) showed lymph nodes, spleen and liver lesions. Axillary lymph node biopsy was performed and the diagnosis of marginal zone lymphoma (MZL) at stage IV was postulated, then the patient was submitted to chemotherapy (CHT) following the R-CVP scheme. After the end of the eighth cycle of CHT he was submitted to a restaging CECT that showed lymph nodes size reduction in all the sites identified on the staging exam. Furthermore the liver lesions disappeared and spleen lesions size was reduced. A whole-body and head 18F-FDG PET/CT was also performed that showed 18F-FDG uptake lesions in right axillary lymph nodes, spleen and liver and the identification of two more extranodal sites, respectively in conjunctiva and skin. Then the necessity of additional CHT cycles and radiotherapy on extranodal sites was postulated. The patient declined the new therapies and unfortunately succumbed four months later. In our case whole body and head 18F-FDG-PET/CT, finding two new extranodal lymphomatous sites and confirming the persistence of the disease, refined and guided the management of the patient suggesting the necessity of additional CHT cycles and radiotherapy on extranodal sites. After histopathological confirmation, a systemic work-up by an oncologist should include whole body and head 18F-FDGPET/ CT to detect possible systemic involvement and guide specific following diagnostic exams.
Journal title :
Iranian Journal of Nuclear Medicine
Journal title :
Iranian Journal of Nuclear Medicine
Serial Year :
2014
Link To Document :
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