Arenas، نويسنده , , Marيa A. and Pérez-Jorge، نويسنده , , Concepciَn and Conde، نويسنده , , Ana and Matykina، نويسنده , , Endzhe and Hernلndez-Lَpez، نويسنده , , Juan M. and Pérez-Tanoira، نويسنده , , Ramَn and de Damborenea، نويسنده , , Juan J. and Gَmez-Barrena، نويسنده , , Enrique and Esteba، نويسنده , , Jaime، نويسنده ,
Ti–6Al–4V joint replacement implants foster uncemented fixation in orthopaedic surgery. However, bacterial colonization competes with host cells and ultimately may produce implant-related difficult-to-treat infections, justifying the efforts to obtain infection-resistant materials. In a previous work, the authors demonstrated the antibacterial properties of anodic fluoride-TiO2 nanostructured layers on Ti–6Al–4V alloy. In this work, the anodizing bath has been modified in order to grow fluoride-TiO2 barrier layers (FBL). A bacterial adherence protocol, run with reference and six different clinical strains of Staphylococcus aureus and Staphylococcus epidermidis, showed a statistically significant decrease in the percentage of covered surface (p < 0.0001, Kruskal–Wallis test) for FBL specimens when compared with non fluoride-containing specimens, i.e. chemically polished Ti–6Al–4V and F-free TiO2 barrier layers. The results obtained on the F-barrier layers allowed discrimination between the effects of the presence of fluoride in the layer and the layer nanostructure on bacterial adhesion.
Surface treatment , Infection , Titanium alloy , bacterial adhesion