Record number :
1883028
Title of article :
Nickel-catalyzed decarboxylative coupling reaction of alkynyl carboxylic acids and allyl acetates
Author/Authors :
Choe، نويسنده , , Juseok and Yang، نويسنده , , Jiyoung and Park، نويسنده , , Kyungho and Palani، نويسنده , , Thiruvengadam and Lee، نويسنده , , Sunwoo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Pages :
5
From page :
6908
To page :
6912
Abstract :
The coupling reaction of aryl alkynyl carboxylic acids and allyl acetates was carried out in the presence of nickel catalyst to produce the allyl alkynes in good yields. The optimized condition is that alkynyl carboxylic acid (1.0 equiv), allyl acetate (2.0 equiv), Ni(OAc)2·4H2O (10 mol %), AgOAc (10 mol %), and zinc (1.0 equiv) were reacted at 100 °C for 0.5 h. In addition, when allyl alcohol was employed instead of allyl acetate, the desired product was obtained in good yield. In addition, when the reaction was carried out in the presence of base such as DBU and Cs2CO3, the allene compounds were formed in good yield.
Keywords :
nickel , Decarboxylative coupling , allylation , Allyl alkyne , Allene
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
Serial Year :
2012
Link To Document :
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