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Title of article :
Specific effects of single antioxidants in the lipid peroxidation caused by nano-titania used in sunscreen lotions
Author/Authors :
Carlotti، نويسنده , , Maria Eugenia and Ugazio، نويسنده , , Elena and Gastaldi، نويسنده , , Lucia and Sapino، نويسنده , , Simona and Vione، نويسنده , , Davide and Fenoglio، نويسنده , , Ivana and Fubini، نويسنده , , Bice، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2009
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Abstract :
The effect of some additives, phenylalanine, ascorbyl palmitate and sodium ascorbyl phosphate on the oxidation of linoleic acid and porcine ear skin induced by UV irradiation was investigated, in the absence and in the presence of variously uncoated and coated titania powders. Such additives have, on the one hand, a scavenging activity toward the oxidizing species photogenerated by TiO2, and on the other one an inhibitory effect toward UVB-induced peroxidation. Sodium ascorbyl phosphate and ascorbyl palmitate displayed a stronger antioxidant effect than phenylalanine toward linoleic acid peroxidation. On porcine skin all the three molecules exhibited both antiradical and antioxidant activity. Their protective effect against peroxidation was higher with porcine skin lipids than with linoleic acid, referable to the chemical differences in the two lipid substrates.
Keywords :
TiO2 Nanoparticles , linoleic acid , Porcine skin , phenylalanine , Ascorbic acid derivatives , UVB irradiation
Journal title :
Journal of Photochemistry and Photobiology B:Biology
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