Record number :
1872085
Title of article :
Highly efficient dynamic kinetic resolution of secondary aromatic alcohols with low-cost and easily available acid resins as racemization catalysts
Author/Authors :
Cheng، نويسنده , , Yongmei and Xu، نويسنده , , Gang and Wu، نويسنده , , Jianping and Zhang، نويسنده , , Chensheng and Yang، نويسنده , , Lirong، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Pages :
4
From page :
2366
To page :
2369
Abstract :
A new and efficient dynamic kinetic resolution (DKR) process of secondary aromatic alcohols was developed with acid resins as racemization catalysts. Acid resin CD8604 was shown to have excellent racemization activity and good biocompatibility. When employing CD8604 and complex acyl donors as racemization catalyst and acyl donor, respectively, enantiomerically pure aromatic acetate was obtained with excellent yield and ee values through the DKR process. It is noteworthy that the system could be reused more than 10 times with little loss of yield and ee value.
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
Serial Year :
2010
Link To Document :
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