Record number :
Title of article :
Preparation of a core–shell type MBHA resin and its application for solid-phase peptide synthesis
Author/Authors :
Choi، نويسنده , , Jeong Hyun and Lee، نويسنده , , Tae-Kyung and Byun، نويسنده , , Jang-Woong and Lee، نويسنده , , Yoon-Sik، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Pages :
From page :
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Abstract :
MBHA (4-methylbenzhydrylamine) resin has been extensively used as a solid support for the synthesis of peptide amides. Herein, we prepared the core–shell-type MBHA resin by benzotriazole-catalyzed amidoalkylation and partial hydrolysis. The core–shell structure of the MBHA resin was confirmed by two-photon microscopy and its synthetic performance in solid-phase peptide synthesis (SPPS) was evaluated.
Keywords :
MBHA resin , Core–shell-type resin , ?-Amidoalkylation , Partial hydrolysis , Solid-phase peptide synthesis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
Serial Year :
Link To Document :