Record number :
1860462
Title of article :
Synthetic studies on the taxane skeleton: effective construction of eight-membered carbocyclic ring by palladium-catalyzed intramolecular α-alkenylation of a methyl ketone
Author/Authors :
Utsugi، نويسنده , , Masayuki and Kamada، نويسنده , , Yasuaki and Nakada، نويسنده , , Masahisa، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Pages :
4
From page :
4754
To page :
4757
Abstract :
A new method for the construction of the eight-membered carbocyclic ring in the taxane skeleton is described. The palladium-catalyzed intramolecular α-alkenylation of a methyl ketone effectively constructed the eight-membered carbocyclic ring in the taxol model compound. To the best of our knowledge, this reaction is the first example of forming an eight-membered carbocyclic ring by the palladium-catalyzed intramolecular α-alkenylation of a ketone.
Journal title :
Tetrahedron Letters
Serial Year :
2008
Link To Document :
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