Record number :
Title of article :
Amberlite-IR 120 catalyzed three-component synthesis of α-amino phosphonates in one-pot
Author/Authors :
Bhattacharya، نويسنده , , Asish K. and Rana، نويسنده , , Kalpeshkumar C.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Pages :
From page :
To page :
Abstract :
A simple, efficient, and environmentally benign method for a three-component reaction of an amine, an aldehyde or a ketone, and diethyl phosphite catalyzed by Amberlite-IR 120 resin has been developed to afford α-amino phosphonates in high yields and short reaction times under solvent-free reaction conditions. The major advantages of the present method are good yields, inexpensive, ecofriendly and reusable catalyst, mild and solvent-free reaction conditions and tolerance towards various functionalities present in the substrates.
Keywords :
Alkyl phosphite , Ion-exchange resin , Multi-component reaction , ?-amino phosphonates , Aldehydes , Amines
Journal title :
Tetrahedron Letters
Serial Year :
Link To Document :