Record number :
1858107
Title of article :
A novel method for the synthesis of 2,2-diaryl-1,1-difluoroethenes
Author/Authors :
Choi، نويسنده , , Ji Hoon and Jeong، نويسنده , , In Howa، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Pages :
4
From page :
952
To page :
955
Abstract :
β,β-Difluoro-α-phenylvinylstannane 3 was prepared in 60% yield from the reaction of β,β-difluoro-α-phenylvinylsulfone 2 with tributyltin hydride in refluxing benzene for 5 h. The cross-coupling reaction of 3 with aryl iodides bearing substituents such as proton, fluoro, chloro, bromo, methoxy, methyl, trifluoromethyl, and nitro on ortho, meta, para positions of the benzene ring in the presence of 10 mol % Pd(PPh3)4/10 mol % CuI afforded the corresponding 2,2-diaryl-1,1-difluoroethenes 4 in 22–82% yields.
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
Serial Year :
2008
Link To Document :
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