Record number :
1843619
Title of article :
A mild and selective method for N-dealkylation of tertiary amines
Author/Authors :
Bhat، نويسنده , , Ramakrishna G. and Ghosh، نويسنده , , Yagnaseni and Chandrasekaran، نويسنده , , Srinivasan، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Pages :
3
From page :
7983
To page :
7985
Abstract :
Alkyl groups can be cleaved efficiently and selectively from tertiary alkyl amines using propargyl chloroformate. The propargyloxycarbonyl (Poc) protected secondary amines thus obtained can be deblocked under neutral and mild conditions using benzyltriethylammonium tetrathiomolybdate. The generality and compatibility of the method have been studied with a wide range of functionalities.
Keywords :
tetrathiomolybdate , N-Dealkylation , Propargyl chloroformate
Journal title :
Tetrahedron Letters
Serial Year :
2004
Link To Document :
بازگشت