Record number :
1824191
Title of article :
Structure of microarc oxidized coatings containing Si, Ca and Na on titanium and deposition of cefazolin sodium/chitosan composite film
Author/Authors :
Cheng، نويسنده , , Su and Wei، نويسنده , , Daqing and Zhou، نويسنده , , Yu، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2011
Pages :
7
From page :
3798
To page :
3804
Abstract :
Microarc oxidized (MAO) coatings containing Si, Ca and Na elements (SCN) were prepared on titanium. The morphology, phase composition and elemental concentrations of the MAO coating surfaces highly depended on the applied voltages. The MAO coatings containing SCN show an atomic concentration gradient along the coating depth. The chemical states of Ti2+, Ti4+, Ca2+, Si2+ and O2− were observed in all the MAO coatings. The novel cefazolin sodium/chitosan composite films were deposited on the MAO coatings for application in therapy of the inflammation resulting from implanting. The increases of depositing times and cefazolin sodium concentration could increase the accumulative release concentration of cefazolin sodium, and could improve the sustaining-release ability of drug film. Also, the addition of chitosan could improve the sustaining-release ability of drug film, indicated that chitosan is a promising delivery carrier for cefazolin sodium.
Keywords :
Cefazolin sodium , Titania , Chitosan , Titanium , Microarc oxidation , Bioactive glass components
Journal title :
Surface and Coatings Technology
Journal title :
Surface and Coatings Technology
Serial Year :
2011
Link To Document :
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