Record number :
1797487
Title of article :
Calcium ionophore A 23187 induces apoptotic cell death in rat thymocytes
Author/Authors :
Azmi، نويسنده , , Sameena and Dhawan، نويسنده , , Deepika and Singh، نويسنده , , Neeta، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Pages :
7
From page :
97
To page :
103
Abstract :
Apoptotic cell death was induced in rat thymocytes on exposure to calcium ionophore A 23187 (100 μm) for 24 h as observed from morphological changes and DNA fragmentation into oligonucleosomal ladder. The cell death was independent of de novo syntheses of protein. However, the involvement of c-Myc, c-Jun, poly ADPR polymerase and antioxidant enzymes CuZn SOD and catalase was observed.
Keywords :
Poly ADPR polymerase , Genes , Thymocytes , apoptosis , Calcium ionophore A 23187
Journal title :
Cancer Letters
Serial Year :
1996
Link To Document :
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