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Title of article :
IrOx–carbon nanotube hybrids: A nanostructured material for electrodes with increased charge capacity in neural systems
Author/Authors :
Carretero، نويسنده , , Nina M. and Lichtenstein، نويسنده , , Mathieu P. and Pérez، نويسنده , , Estela and Cabana، نويسنده , , Laura and Suٌol، نويسنده , , Cristina and Casaٌ-Pastor، نويسنده , , Nieves، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2014
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Abstract :
Nanostructured iridium oxide–carbon nanotube hybrids (IrOx–CNT) deposited as thin films by dynamic electrochemical methods are suggested as novel materials for neural electrodes. Single-walled carbon nanotubes (SWCNT) serve as scaffolds for growing the oxide, yielding a tridimensional structure with improved physical, chemical and electrical properties, in addition to high biocompatibility. In biological environments, SWCNT encapsulation by IrOx makes more resistant electrodes and prevents the nanotube release to the media, preventing cellular toxicity. Chemical, electrochemical, structural and surface characterization of the hybrids has been accomplished. The high performance of the material in electrochemical measurements and the significant increase in cathodal charge storage capacity obtained for the hybrid in comparison with bare IrOx represent a significant advance in electric field application in biosystems, while its cyclability is also an order of magnitude greater than pure IrOx. Moreover, experiments using in vitro neuronal cultures suggest high biocompatibility for IrOx–CNT coatings and full functionality of neurons, validating this material for use in neural electrodes.
Keywords :
Neural electrodes , Coatings , Nanoscaffold , Nanostructuring , Hybrids
Journal title :
Acta Biomaterialia
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