Record number :
Title of article :
First total synthesis of macrosphelides C and F
Author/Authors :
Kobayashi، نويسنده , , Yuichi and Acharya، نويسنده , , Hukum P، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Pages :
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Abstract :
Macrosphelides C and F were synthesized by lactonization of 14-oxo seco acids at the O(10)C(11) bond followed by reduction and Mitsunobu inversion of the resulting hydroxyl group. The seco acids were prepared from the corresponding furans by furan ring-opening with NBS followed by further oxidation of the 4-oxo-2-alkenals with NaClO2.
Keywords :
Furans , macrosphelide F , Macrolides , asymmetric synthesis , macrosphelide C
Journal title :
Tetrahedron Letters
Link To Document :