Record number :
1638265
Title of article :
Synthesis of 18R-hydroxy-epiallo-yohimbines from (−)-3-iso-19,20-dehydro-β-yohimbine: an enantiospecific route to deserpidine and reserpine analogues from secologanin
Author/Authors :
Binns، نويسنده , , Falmai and Brown، نويسنده , , Richard T and Dauda، نويسنده , , Bukar E.N، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Pages :
5
From page :
5631
To page :
5635
Abstract :
(−)-3-Iso-19,20-dehydro-β-yohimbine has been converted into epiallo-yohimbines and, via a novel regio- and stereoselective hydration, into the 18R-hydroxy derivative, an analogue of deserpidine. Its 11-methoxy derivative, also prepared from secologanin, is a potential precursor for a reserpine analogue.
Keywords :
Alkaloids , indole , stereoselection , terpene , Addition reaction , regioselection
Journal title :
Tetrahedron Letters
Link To Document :