Record number :
1638177
Title of article :
Metalation–cyclisation sequence on N-(o-halobenzyl)pyrroles. Synthesis of pyrrolo[1,2-b]isoquinolones
Author/Authors :
Ainhoa Ardeo، نويسنده , , Ainhoa and Lete، نويسنده , , Esther and Sotomayor، نويسنده , , Nuria، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Pages :
4
From page :
5211
To page :
5214
Abstract :
Parham-type cyclisation of N-(o-halobenzyl)pyrroles has been investigated. Aryllithiums generated from metalation of N-(o-iodobenzyl)pyrroles undergo intramolecular cyclisation to give pyrrolo[1,2-b]isoquinolinones in moderate to good yields, if the N,N-diethylcarbamoyl group is used as internal electrophile and the aromatic ring is activated.
Keywords :
pyrroloisoquinolines , pyrroles , lithiation , Cyclisation
Journal title :
Tetrahedron Letters
Serial Year :
2000
Link To Document :
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