Record number :
1637289
Title of article :
Enantioselective synthesis of α-hydroxyacids through oxidation of terminal alkenes with AD-mix/TEMPO
Author/Authors :
F.Javier Aladro، نويسنده , , F and Guerra، نويسنده , , Francisco M and Javier Moreno-Dorado، نويسنده , , F and Bustamante، نويسنده , , Jes?s M and Jorge، نويسنده , , Zacar??as D and Massanet، نويسنده , , Guillermo M، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Pages :
5
From page :
3209
To page :
3213
Abstract :
α-Hydroxyacids can be enantioselectively prepared by means of a two-step oxidation process, involving first the asymmetric dihydroxylation of a terminal alkene and subsequent oxidation with TEMPO/NaOCl/NaClO2 in good to excellent yields. No fragmentation of the glycol intermediate was detected.
Keywords :
Asymmetric dihydroxylation , TEMPO , ?-hydroxyacids , Oxidation
Journal title :
Tetrahedron Letters
Link To Document :