Record number :
1612114
Title of article :
Synthesis of trifluoromethylated 1,5-benzoheteroazepines
Author/Authors :
Christophe، نويسنده , , Carole and Langlois، نويسنده , , Bernard R. and Billard، نويسنده , , Thierry، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2013
Pages :
6
From page :
118
To page :
123
Abstract :
Because of the great interest of benzoheteroazepines and trifluoromethylated compounds in medicinal chemistry, a simple strategy to synthesize trifluoromethylated 1,5-benzoheteroazepines have been described. Starting from β-trifluoromethylated enones and 1,2-diamines or 1,2-thioamines, various benzodiazepines and benzothiazepines bearing a CF3 group have been obtained in good yields.
Keywords :
benzodiazepines , Benzothiazepines , ?-Trifluoromethylated enones , Trifluoromethyl
Journal title :
Journal of Fluorine Chemistry
Link To Document :