Record number :
1513291
Title of article :
Applications of Hadamard transform-gas chromatography/mass spectrometry to online detection of exhaled breath after drinking or smoking
Author/Authors :
Cheng، نويسنده , , Yuan-Kai and Lin، نويسنده , , Cheng-Huang and Kaneta، نويسنده , , Takashi and Imasaka، نويسنده , , Totaro، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2010
Pages :
5
From page :
5274
To page :
5278
Abstract :
A Hadamard transform-gas chromatography/mass spectrometry (HT-GC/MS) technique was employed for the online detection of ethanol or toluene in exhaled breath after drinking or smoking, respectively. Exhaled breath samples, collected from volunteers, were directly injected into the GC inlet by a Hadamard-injector without any pretreatment. In the case of breath from a drinker, using a conventional single injection, a small ion peak (corresponding to ∼0.1 ng of ethanol), the intensity of which was approximately equal to or less than the limit of detection. When the HT technique was applied, the signal-to-noise (S/N) ratio was dramatically improved. Furthermore, in the case of breath from a smoker, using conventional injection, a weak ion peak (corresponding to ∼0.7 pg of toluene) was marginally detected. However, the HT technique led to an improvement in the S/N ratio, with the peak corresponding to the limit of detection. In both cases, the HT technique permitted specific components in exhaled breath to be determined, without the need for any extraction procedures.
Keywords :
Exhaled breath , Smoking , drinking , HT-GC/MS
Journal title :
Journal of Chromatography A
Journal title :
Journal of Chromatography A
Serial Year :
2010
Link To Document :
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