Record number :
1304792
Title of article :
Synthesis and structure–activity relationships of 2-alkylidenethiazolidine-4,5-diones as antibiotic agents Original Research Article
Author/Authors :
Uwe Albrecht، نويسنده , , Dirk G?rdes، نويسنده , , Enrico Schmidt، نويسنده , , Kerstin Thurow، نويسنده , , Michael Lalk، نويسنده , , Peter Langer، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Pages :
6
From page :
4402
To page :
4407
Abstract :
2-Alkylidenethiazolidine-4,5-diones were prepared by novel one-pot cyclizations of arylacetonitriles with isothiocyanates and ethyl 2-chloro-2-oxoacetate. The products show antibiotic activity against the Gram-positive bacteria Bacillus subtilis and Staphylococcus aureus.
Keywords :
Antibiotics , Cyclizations , Heterocycles , Isothiocyanates , thiazolidines
Journal title :
Bioorganic and Medicinal Chemistry
Link To Document :