Title of article :
Friend or Foe? Turning a Host Defense Protein Into a Pathogenʹs Accomplice
Aimee Shen، نويسنده , , Matthew Bogyo، نويسنده ,
Issue Information :
ماهنامه با شماره پیاپی سال 2008
Cystatins are cysteine protease inhibitors that are at the front-line of defense against pathogens that secrete proteases as virulence factors. In this issue, reveal how the bacterial protease IdeS from Streptococcus pyogenes hijacks normal cystatin C function to convert it into a cofactor that enhances proteolytic destruction of host-defense antibodies.
Journal title :
Chemistry and Biology