Record number :
1105328
Title of article :
Vinyl selenones: annulation agents for the synthesis of six-membered benzo-1,4-heterocyclic compounds
Author/Authors :
Luana Bagnoli، نويسنده , , Sara Casini، نويسنده , , Francesca Marini، نويسنده , , Claudio Santi، نويسنده , , Lorenzo Testaferri، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Pages :
6
From page :
481
To page :
486
Abstract :
A novel and general approach to six-membered bicyclic benzo fused 1,4-heterocycles is described. The addition–cyclization cascade of benzo 1,2-diols, 1,2-thiols and 2-(benzylamino)phenols with stable and easily available vinyl selenones affords differently substituted 2,3-dihydro-1,4-benzodioxines, benzodithiines and 3,4-dihydro-2H-1,4-benzoxazines in good yields. The same procedure has been extended to the synthesis of 1,2,3,4-tetrahydroquinoxalines. All of these heterocycles are present in a variety of biologically active compounds.
Keywords :
1 , 4-benzoxazines , Vinyl selenones , 1 , 4-benzodioxines , MIRC reaction , 1 , 4-Benzothiines
Journal title :
Tetrahedron
Link To Document :