Title of article :
A Mild and Efficient Synthesis of 2,5-Disubstituted 2,3-Dihydro-4pyridones Catalyzed by Yb(OTf)3
Cheng، Jie-Ke نويسنده , , Gao، Bo نويسنده , , Feng، Xiaoming نويسنده , , Zeng، Baiqing نويسنده , , Yu، Zhipeng نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
A highly efficient aza-Diels-Alder reaction of trans-1-methoxy-2-methyl-3trimethylsiloxybuta-1,3-diene with N-benzhydryl imines was catalyzed by Yb(OTf)3 in toluene at room temperature to give corresponding 2,5disubstituted 2,3-dihydro-4-pyridones in high yields. Three-component reactions of diene with aldehydes and amines were also performed smoothly to afford the desired cycloadducts under solvent-free condition in 51-86% yields.
Lewis acid , three-component reaction , N-benzhydryl imines , solvent-free , Diels-Alder reaction