Title of article :
SIRT3 in Calorie Restriction: Can You Hear Me Now?
Carlos Sebastian، نويسنده , , Raul Mostoslavsky، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Caloric restriction decreases oxidative damage and extends life span in many organisms. show that the sirtuin SIRT3 mediates the protective effects of caloric restriction on age-related hearing loss by promoting the mitochondrial antioxidant system through the regulation of isocitrate dehydrogenase 2 (Idh2).